Cat NPC2, a Newly Identified Allergen, With High Cross-Reactivity to Can f 7
نویسندگان
چکیده
منابع مشابه
Assessment of allergen cross-reactivity
The prediction of allergen cross-reactivity is currently largely based on linear sequence data, but will soon include 3D information on homology among surface exposed residues. To evaluate procedures for these predictions, we need ways to quantitatively assess actual cross-reactivity between two allergens. Three parameters are mentioned: 1) the fraction of the epitopes that is cross-reactive; 2...
متن کاملCommentary Assessment of allergen cross - reactivity
The prediction of allergen cross-reactivity is currently largely based on linear sequence data, but will soon include 3D information on homology among surface exposed residues. To evaluate procedures for these predictions, we need ways to quantitatively assess actual cross-reactivity between two allergens. Three parameters are mentioned: 1) the fraction of the epitopes that is cross-reactive; 2...
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Pets are an important source of indoor allergens. The aim of the study was to compare cat and dog allergen levels in cars, schools and homes. The study was carried out in 17 cars, 14 classrooms and 19 dwellings located in the highly industrialized and urbanized region of Poland. Dust and air samples were analyzed for Fel d 1 and Can f 1 using a double monoclonal ELISA assay. The highest amounts...
متن کاملBarnacle allergy: allergen characterization and cross-reactivity with mites.
BACKGROUND Barnacles are a type of seafood with worldwide distribution and abundant along the shores of temperate seas. They are particularly appreciated and regularly consumed in Portugal as well as in Spain, France and South America, but barnacle allergy is a rare condition of which there is only one reference in the indexed literature. The molecular allergens and possible cross-reactivity ph...
متن کاملIgE Reactivity of the Dog Lipocalin Allergen Can f 4 and the Development of a Sandwich ELISA for Its Quantification
PURPOSE Divergent results on the IgE reactivity of dog-allergic subjects to Can f 4 have been reported. The aim of this study was to evaluate the significance of Can f 4 in dog allergy and to develop an immunochemical method for measuring Can f 4 content in environmental samples. METHODS We purified the natural dog allergen Can f 4 from a dog dander extract by monoclonal antibody-based affini...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2021
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2021.13.1.122